Sep 062013
 September 6, 2013

skin cancer disease marijuana cannabisCourtesy of The Joint Blog

new study, recently published online in the British Journal of Pharmacology, details how cannabinoids can play a role in the treatment of skin diseases.

Researchers looked at the impact of phytocannabinoids (plant-derived cannabinoids, rather than synthetic counterparts) on epigenetic regulation of skin differentiation genes.

The study found that both cannabidiol (CBD) and cannabigerol (CBG), “significantly reduced the expression of all genes tested via increased DNA methylation for keratin 10 gene”.

The CBD was found to reduce keratin 10 mRNA through stimulating type-1 cannabinoid (CB1) receptors, while the CBG was found to act through a secondary method that did not engage the CB1 or CB2 receptors of keratinocytes (HaCaT cells). It was also revealed that cannabidiol increased global DNA methylation levels.

The study concludes that cannabis could act as a primary treatment for epidermal ailments:

“These findings identify the phytocannabinoids cannabidiol and cannabigerol as transcriptional repressors that can control cell proliferation and differentiation, suggesting (especially for cannabidiol) a possible exploitation as lead compounds to be used in the development of novel therapeutics for skin diseases.”

This report was conducted by researchers at the University of Teramo, the Campus Bio-Medico University and the Santa Lucia Foundation, all located in Italy.

Source: TheJointBlog.Com

About Johnny Green

Johnny Green is a marijuana activist from Oregon. He has a Bachelor's Degree in Public Policy. Follow Johnny Green on Facebook and Twitter. Also, feel free to email any concerns.
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  • Rhea Graham

    We’ve noticed that at Albany’s Canna Kitchen & Research, LLC. Our Super Salve and Face Oil both do incredible things for the skin! Seriously noticeable, positive differences just to the casual observer. This is an amazing plant and I look forward to when it is set free to heal the people!

  • Codes

    Does it counteract the effects of psoriasis? If a treatment could be derived from this plant for that affliction then this is truly gods biggest gifts to man. We must use it!

    • Rhea Graham

      Yes, it does!!!

  • Lisa

    I’ve got eczema on my fingertips, which is very hard to live with. It handicaps me in a myriad of ways. If CBD and CBG can help, I’d be forever grateful!

    • Rhea Graham

      Definitely, you need to get some salve going on, you will be amazed!

    • Rev_Lowrey

      I suffered eczema on my hands for over 20 years and never could get rid of it on my fingertips. When I gave up my 25 year vegan diet and went grain-free it all cleared up completely. (and almost immediately) Try a month without grain.

      I have used canna-oil to eliminate moles and warts. A friend quite dramatically healed a cancer on his nose and I have also used it to heal a dry and dark patch of sun damage on my nose. Several of my acquaintances have used it successfully to heal skin problems that seemed untreatable.

  • Cheryl Sparks

    Maybe why since I started smoking again my Lupus lesions have decreased so much ;-) Sucks to be considered “beautiful for someone who looks like a leper” as once told me during a really bad SLE flare :-/

  • freckles

    I have sweet’s syndrome short for Acute febrile neutrophilic dermatosis which is a very rare autoimmune dermatologic skin disorder and would like to know if medical marijuana or hemp oil / other topicals have helped anyone with a similar autoimmune skin disorder. If so what types or doses help. 24 years of this disease and I keep looking for answers to reduce flares.